Antibacterial liquid soap help prevent the infection of pathogenic bacteria, such as S. aureusand E. coli that can cause skin infection and diarrhea. Red ginger is one of natural plants that hasthe potential as an antibacterial agent in soaps and also known to have antibacterial activity. Soap isformed from the reaction between a fattty acid and base so its quality is affected by the perfection ofthat reaction. The purpose of this study was to determine the optimum composition of VCO andKOH using Simplex Lattice Design (SLD) and its physicochemical properties. The extraction wasdone by soxletation method using ethanol 96%. Antibacterial test showed that the optimumconcentration of the extract was 50 mg/mL. Soap with variation of the VCO and KOH had specificgravity 0,955-1,045; viscosity 0,3-2,1; pH 9,366-10,566; and free alkali 7,48x10%.The composition of the VCO and KOH that predicted by SLD is 26,386 g VCO and 6,414 g KOH.This optimum formula had specific gravity 1.03148; viscosity 0.723; pH 10,066; and 0.0086% freealkali. Independent two-sample test between the physicochemical properties resulted from the testand results predicted by SLD showed no significant difference (p>0,05). The antibacterial activityof optimum formula didn\u27t differ significantly with the control (p>0,05).
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机译：抗菌液体肥皂有助于防止可能引起皮肤感染和腹泻的病原细菌（如金黄色葡萄球菌和大肠杆菌）的感染。红姜是天然植物中的一种，具有在肥皂中用作抗菌剂的潜力，并且还具有抗菌活性。肥皂是由脂肪酸与碱之间的反应形成的，因此其质量受该反应的完善性影响。这项研究的目的是使用单晶格设计（SLD）来确定VCO和KOH的最佳组成及其理化性质。通过使用96％乙醇的索氏提取法进行提取。抗菌测试表明提取物的最佳浓度为50 mg / mL。 VCO和KOH变化的肥皂的比重为0,955-1,045；粘度0,3-2,1; pH值9,366-10,566; SLD预测的VCO和KOH的组成分别为26,386 g VCO和6,414 g KOH。该最佳公式的比重为1.03148。粘度0.723； pH值10,066;和0.0086％的游离碱。由测试得出的理化性质与SLD预测的结果之间的独立两样本测试无显着性差异（p> 0.05）。最佳配方的抗菌活性与对照组无显着性差异（p> 0.05）。
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